Inheritance of perturbed methylation and metabolism caused by uterine malnutrition via oocytes.

Shou-Bin TangTing-Ting ZhangShen YinWei ShenShi-Ming LuoYong ZhaoCui-Lian ZhangFrancesca Gioia KlingerQing-Yuan SunZhao-Jia Ge

Published in: BMC biology (2023)

These results indicate that DNA methylation may mediate the transgenerational inheritance of metabolic disorders induced by undernourishment in utero via female germline.

Keyphrases

dna methylation
mitochondrial dna
genome wide
copy number
gene expression
dna repair