Emulation of the control cohort of a randomized controlled trial in pediatric kidney transplantation with Real-World Data from the CERTAIN Registry.
Christian PatryLukas D SauerAnja SanderKai KrupkaAlexander FichtnerJolanda BrezinskiYvonne GeissbühlerElodie AubrunAnna GrinienkoLuca Dello StrologoDieter HaffnerJun OhRyszard GrendaLars PapeRezan TopaloğluLutz Thorsten WeberAntonia BoutsJon Jin KimAgnieszka PrytulaJens KönigMohan ShenoyBritta HöckerBurkhard TönshoffPublished in: Pediatric nephrology (Berlin, Germany) (2022)
In conclusion, usage of Real-World Data from patient registries such as CERTAIN to emulate the control cohort of an RCT is feasible and could facilitate the conduct of clinical trials in pediatric kidney transplantation. A higher resolution version of the Graphical abstract is available as Supplementary information.