BAP31 Promotes Adhesion Between Endothelial Cells and Macrophages Through the NF-κB Signaling Pathway in Sepsis.
Jiawei HeDanyang JingShen ZhaoMeili DuanPublished in: Journal of inflammation research (2024)
BAP31 up-regulated the expressions of ICAM1 and VCAM1 in endothelial cells leading to sepsis-associated organ injury. This may be involved in activation of TLR signaling pathway, TAK1 pathway, and PI3K-AKT signaling pathway.
Keyphrases
- pi k akt
- signaling pathway
- endothelial cells
- cell cycle arrest
- cell proliferation
- epithelial mesenchymal transition
- induced apoptosis
- acute kidney injury
- intensive care unit
- septic shock
- high glucose
- inflammatory response
- toll like receptor
- immune response
- transcription factor
- vascular endothelial growth factor
- cystic fibrosis
- escherichia coli
- staphylococcus aureus
- lps induced
- candida albicans