Influence of oxytocin receptor single nucleotide sequence variants on contractility of human myometrium: an in vitro functional study.

F FüegS SantosC HaslingerB StoiberL SchäfferE GrünblattR ZimmermannAna Paula Simões-Wüst

Published in: BMC medical genetics (2019)

Patients with variant alleles of rs237888 and/or rs4686302 may be more sensitive to oxytocin stimulation, explaining why these sequence variants have been associated with lower cesarean section prevalence and premature birth, respectively.

Keyphrases

copy number
endothelial cells
risk factors
induced pluripotent stem cells
gestational age
pregnant women
genome wide