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Thermal energy and tableting effects in benznidazole product: the impacts of industrial processing.

Maria Betânia de Freitas-MarquesTalita Santos do ValleBárbara Caroline Rodrigues de AraujoRita de Cássia de Oliveira SebastiãoWagner da Nova MusselMaria Irene YoshidaChristian Fernandes
Published in: Drug development and industrial pharmacy (2023)
These results indicate the necessity of considering the thermal energy and tableting effects of BZN manufacturing, which contributes significantly to the molecular mechanistic understanding of this drug delivery system.
Keyphrases
  • heavy metals
  • trypanosoma cruzi
  • single molecule
  • risk assessment