Citrulline Not a Major Determinant in the Recognition of Peptidylarginine Deiminase 2 and 4 by Autoantibodies in Rheumatoid Arthritis.
Erika DarrahRyan L DavisAshley M CurranPooja NaikRuiqiang ChenChan Hyun NaJon T GilesFelipe AndradePublished in: Arthritis & rheumatology (Hoboken, N.J.) (2020)
Autocitrullination does not affect autoantibody reactivity to PADs in the majority of patients with RA, demonstrating that anti-PAD antibodies are distinct from anti-citrullinated protein antibodies in their dependence on citrullination for binding.