Previous Drug Exposure in Patients Hospitalised for Acute Liver Injury: A Case-Population Study in the French National Healthcare Data System.
Nicholas MooreStéphanie DuretAdeline GrolleauRégis LassalleVanessa BarbetMai DuongNicolas ThurinCécile Droz-PerroteauSinem Ezgi GulmezPublished in: Drug safety (2020)
This nationwide study describes drugs associated with ALI, according to absolute population burden and per-patient and per-tablet risk. Some of these associations may be spurious, others causal, and others yet were unexpected. Systematic analysis of drug classes will look for outliers within each class that could raise signals of unexpected hepatic toxicity.
Keyphrases
- drug induced
- liver injury
- healthcare
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- adverse drug
- prognostic factors
- oxidative stress
- peritoneal dialysis
- liver failure
- case report
- big data
- quality improvement
- respiratory failure
- intensive care unit
- emergency department
- patient reported outcomes
- hepatitis b virus
- risk factors
- deep learning
- social media
- health insurance
- health information