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Unravelling the hidden ancestry of American admixed populations.

Francesco MontinaroGeorge B J BusbyVincenzo L PascaliSimon MyersGarrett HellenthalCristian Capelli
Published in: Nature communications (2015)
The movement of people into the Americas has brought different populations into contact, and contemporary American genomes are the product of a range of complex admixture events. Here we apply a haplotype-based ancestry identification approach to a large set of genome-wide SNP data from a variety of American, European and African populations to determine the contributions of different ancestral populations to the Americas. Our results provide a fine-scale characterization of the source populations, identify a series of novel, previously unreported contributions from Africa and Europe and highlight geohistorical structure in the ancestry of American admixed populations.
Keyphrases
  • genome wide
  • genetic diversity
  • dna methylation
  • air pollution
  • gene expression
  • machine learning
  • genome wide association study
  • artificial intelligence
  • copy number
  • deep learning