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Dansyl acetyl trehalose: a novel tool to investigate the cellular fate of trehalose.

Alessandra LocatelliLuisa IommariniAlessandra GraziadioAlberto LeoniAnna Maria PorcelliStefano IottiEmil MalucelliFrancesco FranciaGiovanni VenturoliGiovanna Farruggia
Published in: RSC advances (2019)
A fluorescent derivative of trehalose with two dansyl groups (DAT) has been synthesized. It is characterised by a large Stokes shift, good permeability in human living cells and a well detectable fluorescent signal within the cells. Notably, in intestinal cells DAT is sequestered in vesicles induced by trehalose pre-treatment and colocalizes with lipid droplets.
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