Immune and metabolic perturbations in COVID-19-associated pulmonary mucormycosis: A transcriptome analysis of innate immune cells.
Manpreet DhaliwalValliappan MuthuArunima SharmaKhem RajShivaprakash Mandya RudramurthyRitesh AgarwalHarsimran KaurAmit RawatSurjit SinghArunaloke ChakrabartiPublished in: Mycoses (2024)
We identified significant alterations in the metabolic pathways possibly leading to cellular iron overload and a hyperglycaemic state. Immune responses revealed altered recognition, signalling, effector functions and a pro-inflammatory state in monocytes and neutrophils from CAPM patients.