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Serum neurofilament light chain as a surrogate of cognitive decline in sporadic and familial frontotemporal dementia.

Anuschka Silva-SpínolaMarisa LimaMaria João LeitãoJoão DurãesMiguel Tábuas-PereiraMaria Rosário AlmeidaIsabel SantanaInês Baldeiras
Published in: European journal of neurology (2021)
Our findings highlight the potential of serum NfL as a useful surrogate end point of disease severity in upcoming targeted treatments.
Keyphrases
  • cognitive decline
  • mild cognitive impairment
  • late onset
  • early onset
  • cerebrospinal fluid
  • cancer therapy
  • amyotrophic lateral sclerosis