Musculoskeletal manifestations occur predominantly in patients with later-onset familial Mediterranean fever: Data from a multicenter, prospective national cohort study in Japan.
Yushiro EndoTomohiro KogaMidori IshidaYuya FujitaSosuke TsujiAyuko TakataniToshimasa ShimizuRemi SumiyoshiTakashi IgawaMasataka UmedaShoichi FukuiAyako NishinoShin-Ya KawashiriNaoki IwamotoKunihiro IchinoseMami TamaiHideki NakamuraTomoki OriguchiKazunaga AgematsuAkihiro YachieJunya MasumotoKiyoshi MigitaAtsushi KawakamiPublished in: Arthritis research & therapy (2018)
Our results indicate that the later-onset FMF patients had a lower percentage of MEFV mutations in exon 10 and predominantly presented arthritis and myalgia. It is important to distinguish their FMF from other inflammatory diseases.