Maintenance therapy with partially hydrolyzed guar gum in the conservative treatment of chronic anal fissure: results of a prospective, randomized study.
Antonio BrillantinoFrancesca IacobellisGiuseppe IzzoNatale Di MartinoRoberto GrassiAdolfo RenziPublished in: BioMed research international (2014)
The maintenance therapy with PHGG in patients with healed CAF after chemical sphincterotomy by topical application of GTN 0.4% ointment seems associated with a significant reduction of recurrence rate and with a significant increase of success rate at 12-month followup.