Pre-existing Interstitial Lung Abnormalities and Immune Checkpoint Inhibitor-Related Pneumonitis in Solid Tumors: A Retrospective Analysis.
Kohei HoriuchiShinnosuke IkemuraTakashi SatoKeitaro ShimozakiSatoshi OkamoriYoshitake YamadaYoichi YokoyamaMasahiro HashimotoMasahiro JinzakiIkuko HiraiTakeru FunakoshiRyuichi MizunoMototsugu OyaKenro HirataYasuo HamamotoHideki TeraiHiroyuki YasudaIchiro KawadaKenzo SoejimaKoichi FukunagaPublished in: The oncologist (2023)
This retrospective study did not demonstrate statistically significant association between pre-existing ILA and ICI-related pneumonitis, nor an association between radiologic features of ILA and ICI-related pneumonitis. Smoking history was independently associated with ICI-related pneumonitis. Further research is warranted for further understanding of the risk factors of ICI-related pneumonitis.