Segmentation of the Globus Pallidus Internus Using Probabilistic Diffusion Tractography for Deep Brain Stimulation Targeting in Parkinson Disease.
Erik H MiddlebrooksIbrahim Sacit TunaSanjeet S GrewalLeonardo AlmeidaMichael G HeckmanElizabeth R LesserKelly D FooteMichael S OkunVanessa Milanese Holanda ZimpelPublished in: AJNR. American journal of neuroradiology (2018)
In this pilot study, we assessed a novel method of segmentation of the globus pallidus internus based on probabilistic tractography as a supplement to traditional targeting methods. Our results suggest that our method may be an independent predictor of deep brain stimulation outcome, and evaluation of a larger cohort or prospective study is warranted to validate these findings.