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Posttransplant cyclophosphamide versus antithymocyte globulin in patients with acute lymphoblastic leukemia treated with allogeneic hematopoietic cell transplantation from matched unrelated donors. A study from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation.

Sebastian GiebelMyriam LabopinUrpu SalmenniemiGerard SociéSergey BondarenkoDidier BlaiseNicolaus KrögerJan VydraAnna GrassiFrancesca BonifaziTomasz CzerwAchilles AnagnostopoulosBruno LioureAnnalisa RuggeriBipin SavaniAlexandros SpyridonidisJaime SanzZinaida PericArnon NaglerFabio CiceriMohamad Mohty
Published in: Cancer (2023)
The receipt of ATG compared with PTCY, despite the reduced risk of extensive chronic GVHD, is associated with inferior LFS in adults with ALL who undergo hematopoietic cell transplantation from 10/10 human leukocyte antigen-matched unrelated donors. These findings warrant verification in prospective trials.
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