Preoperative Radiotherapy with a Simultaneous Integrated Boost Compared to Chemoradiotherapy for cT3-4 Rectal Cancer: Long-Term Results of a Multicenter Randomized Study.
Benedikt EngelsAntonino De PaoliElena DelmastroFernando MunozStefano VaggeDarius NorkusHendrik EveraertGianna TabaroElisabetta GariboldiUmberto RicardiEugenio BorsattiPietro GabrieleRoberto InnocenteElisa PalazzariEmilie DubaereMarc-André MahéSven Van LaereThierry GevaertMark De RidderPublished in: Cancers (2023)
The preoperative RTSIB approach was not inferior to CRT in terms of metabolic response, toxicity, OS, PFS and LC, and could be considered an available option for patients unfit for fluorouracil-based CRT.
Keyphrases
- rectal cancer
- locally advanced
- end stage renal disease
- patients undergoing
- newly diagnosed
- ejection fraction
- chronic kidney disease
- early stage
- radiation therapy
- peritoneal dialysis
- squamous cell carcinoma
- cardiac resynchronization therapy
- clinical trial
- magnetic resonance
- radiation induced
- simultaneous determination
- patient reported outcomes
- contrast enhanced
- dual energy
- patient reported
- atrial fibrillation
- liquid chromatography