Doppler ultrasound to assess the pharmacodynamic effects of splanchnic vasoactive compounds.
Heleen MarynissenThomas LodeweyckxDidier BielenJan N de HoonPublished in: British journal of clinical pharmacology (2021)
Doppler ultrasound is a reproducible method for flow measurements in the superior mesenteric artery in a standardized group of healthy volunteers. Therefore, it is a promising technique to assess pharmacodynamic effects of splanchnic vasoactive compounds in early clinical drug development.