Anatomical and functional changes in the retina in patients with Alzheimer's disease and mild cognitive impairment.
Stephan SzegediPeter Dal-BiancoElisabeth StögmannTatjana Traub-WeidingerMichael RainerAndreas MaschingDoreen SchmidlRené M WerkmeisterJacqueline ChuaLeopold SchmettererGerhard GarhöferPublished in: Acta ophthalmologica (2020)
In patients with MCI and AD, arteriovenous difference in oxygen saturation, retinal blood flow and arterial vessel diameter was reduced. No difference was found in flicker response between groups. This indicates alterations in retinal oxygen metabolism in patients with neurodegenerative disease.