The (apparent) antibody paradox in COVID-19.
Rohan AmeratungaSee-Tarn WoonEdward LeaRichard SteeleKlaus LehnertEuphemia Y LeungAnna E S BrooksPublished in: Expert review of clinical immunology (2022)
These observations suggest T cell responses to SARS-CoV-2 are the dominant long-term protective mechanism following either infection or vaccination. The magnitude and quality of the antibody response is likely to reflect underlying T cell immunity to SARS-CoV-2. Much of what has been learned about COVID-19 will need to be revised following the recent rapid emergence and dominance of the omicron variant of SARS-CoV-2.