Novel clinical and immunological features associated with persistent post-acute sequelae of COVID-19 after six months of follow-up: a pilot study.
Jiram Torres-RuizJulieta Lomelín-GascónJaquelin Lira LunaAna Sofia Vargas-CastroAlfredo Pérez-FragosoMiroslava Nuñez-AguirreBeatriz Alcalá-CarmonaAbdiel Absalón-AguilarJennifer T Balderas-MirandaJosé Luis Maravillas-MonteroNancy R Mejía-DomínguezCarlos Núñez-ÁlvarezLuis LlorenteSandra Romero-RamírezVictor Andrés Sosa-HernándezRodrigo Cervantes-DíazGuillermo Juárez-VegaDavid Meza-SánchezMarina Rull-GabayetLuis Alberto Martínez-JuárezLinda MoralesLizeth Naomi López-LópezJosé Adrián Negrete-TrujilloJorge Abelardo Falcón-LezamaRafael Ricardo Valdez-VázquezHéctor Gallardo-RincónRoberto Tapia-ConyerDiana Gómez-MartínPublished in: Infectious diseases (London, England) (2023)
Our data suggest an important relationship between a pro-inflammatory state mediated through metabolic pathways related to obesity and increased cellular senescence as a key element in the persistence of post-COVID-19 syndrome at six months of follow-up.
Keyphrases
- coronavirus disease
- sars cov
- liver failure
- metabolic syndrome
- insulin resistance
- type diabetes
- weight loss
- electronic health record
- dna damage
- respiratory failure
- respiratory syndrome coronavirus
- drug induced
- endothelial cells
- weight gain
- high fat diet induced
- adipose tissue
- body mass index
- intensive care unit
- skeletal muscle
- mechanical ventilation
- extracorporeal membrane oxygenation