Thyroid hormone homeostasis in levothyroxine-treated patients: Findings from ELSA-Brasil.

Gustavo Cancela E PennaIsabela M BensenorAntonio Carlos Bianco Matthew D Ettleson

Published in: The Journal of clinical endocrinology and metabolism (2024)

The present results challenge the dogma that treatment with LT4 for hypothyroidism restores TH homeostasis in all patients. A substantial number of LT4-treated patients exhibit repeated FT4 and FT3 levels outside the normal reference range, despite normal TSH levels. Further studies are needed to define the clinical implications of these findings.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
patient reported outcomes
combination therapy