Discovery of new drug indications for COVID-19: A drug repurposing approach.

Priyanka Kumari Bikram Pradhan Maria Koromina George P PatrinosKristel Van Steen

Published in: PloS one (2022)

Our drug similarity model highlighted ten drugs, including reference drugs that can act as potential therapeutics against SARS-CoV-2. The docking results suggested that doxorubicin showed the least binding energy compared to reference drugs. Their practical utility as anti-SARS-CoV-2 drugs, either individually or in combination, warrants further investigation.

Keyphrases

sars cov
drug induced
respiratory syndrome coronavirus
small molecule
coronavirus disease
adverse drug
emergency department
molecular dynamics
high throughput
transcription factor
electronic health record
dna binding
binding protein