Aspherical and Spherical InvA497-Functionalized Nanocarriers for Intracellular Delivery of Anti-Infective Agents.

Arianna CastoldiMartin EmptingChiara De RossiKarsten MayrPetra DerschRolf HartmannRolf MüllerSarah GordonClaus-Michael Lehr

Published in: Pharmaceutical research (2018)

InvA497-functionalized, polymer-based nanocarriers were able to efficiently deliver a non-permeable antibiotic across host cell membranes to affect killing of intracellular bacteria. Functionalized nanocarriers with an aspherical shape showed an interesting future potential for intracellular infection therapy.

Keyphrases

drug delivery
drug release
quantum dots
cancer therapy
reactive oxygen species
molecularly imprinted
single cell
cell therapy
current status
risk assessment
mass spectrometry