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Effects of maturation and size on population pharmacokinetics of pentoxifylline and its metabolites in very preterm infants with suspected late-onset sepsis or necrotizing enterocolitis: a pilot study incorporating clinical outcomes.

Sam SalmanJulie HibbertMadhu Page-SharpLaurens ManningKaren SimmerDorota A DohertySanjay PatoleKevin T BattyTobias Strunk
Published in: British journal of clinical pharmacology (2018)
The developed model can be used to explore dosing strategies based on size and maturation for preterm infants.
Keyphrases
  • preterm infants
  • late onset
  • low birth weight
  • early onset
  • ms ms
  • acute kidney injury
  • intensive care unit
  • pulmonary embolism
  • septic shock