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Characteristic of IgA and IgG antibody response to SARS-CoV-2 infection in an Italian referral COVID-19 Hospital.

Annamaria CarnicelliBarbara FioriRosalba RicciAlfonso PianoNicola BonadiaEleonora TaddeiMassimo FantoniRita MurriAntonella CingolaniChristian BarillaroSalvatore Lucio CutuliDebora MarchesiniDavide Antonio Della PollaEvelina ForteMariella FuorloLuca Di MaurizioPaola AmoriniPaola CattaniFrancesco FranceschiMaurizio Sanguinetti
Published in: Internal and emergency medicine (2021)
IgA and IgG antibody response is closely related, although seroconversion for IgA occurs earlier. Both IgA and IgG are maintained beyond 2 months. Severe patients showed a more vigorous IgA and IgG response. IgA levels seem to decline after 1 month since the onset of symptoms in mild cases. Our results should be interpreted with cautions due to several limitations in our study, mainly the small number of cases, lack of data on viral load and clinical setting.
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