Analysis of imaging biomarkers and retinal nerve fiber layer thickness in RPGR-associated retinitis pigmentosa.

Theresa H BirtelJohannes BirtelKristina HessAmelie C ClemensMoritz LindnerPhilipp HerrmannFrank G HolzMartin Gliem

Published in: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie (2021)

This study describes retinal characteristics in patients with RPGR-associated RP including a pronounced peripapillary RNFL thickness compared to healthy controls. These results contribute to the knowledge about imaging biomarkers in RP, which might be of interest for therapeutic approaches such as gene replacement therapies.

Keyphrases

optical coherence tomography
diabetic retinopathy
high resolution
optic nerve
healthcare
genome wide
copy number
gene expression
mass spectrometry
dna methylation
transcription factor