Association of common IL-10 promoter gene variants with the susceptibility to head and neck cancer in Tunisia

Lamia Maknı Cherif Ben Hamda Abrar Al-ansarı Oussema Souiai Ezzedine Gazouanı Amel Mezlını Wassim Y Almawi Basma Yaacoubi-Loueslati

Published in: Turkish journal of medical sciences (2019)

Our results demonstrate that IL-10-1082, IL-10-819, and IL-10-592 variants, and haplotypes GC and GT constitute biomarkers for early detection of HNC, especially NPC subtype. IL-10 -819T/C and TA haplotype may be used as biomarkers for early detection of LC.

Keyphrases

copy number
dna methylation
gene expression
genome wide
mass spectrometry
high resolution