Feasibility of performing a multi-arm clinical trial examining the novel combination of repetitive transcranial magnetic stimulation and aerobic exercise for post-stroke depression.

Ryan E Ross Catherine J VanDerwerkerMark S GeorgeChris M Gregory

Published in: Topics in stroke rehabilitation (2023)

Performing a multi-arm combinatorial trial examining the effect of rTMS+AEx on PSD appears feasible. All treatment arms demonstrated strong adherence to their respective interventions and were well received. rTMS and the combination of AEx with rTMS may be alternative treatments for PSD.

Keyphrases

transcranial magnetic stimulation
high frequency
clinical trial
phase ii
phase iii
study protocol
depressive symptoms
physical activity
open label
sleep quality
type diabetes
combination therapy
adipose tissue
insulin resistance
weight loss