Association between Neuron-Specific Enolase, Memory Function, and Postoperative Delirium after Transfemoral Aortic Valve Replacement.
Jonathan NübelCharlotte BuhreMeike HoffmeisterStefanie OessOliver LabrenzKerstin JostMichael HauptmannJulika SchönGeorg FritzChristian ButterAnja Haase-FielitzPublished in: Journal of cardiovascular development and disease (2023)
Memory function improved after TAVR, likely due to learning effects, with no association to change in NSE. Patients with POD appear to have significantly higher postoperative levels of NSE compared to patients without POD after TAVR. This finding suggests that neuronal damage, as indicated by NSE elevation, may not significantly impair assessed memory function after TAVR.
Keyphrases
- aortic stenosis
- aortic valve replacement
- ejection fraction
- aortic valve
- transcatheter aortic valve replacement
- transcatheter aortic valve implantation
- working memory
- end stage renal disease
- patients undergoing
- left ventricular
- chronic kidney disease
- newly diagnosed
- coronary artery disease
- cardiac surgery
- oxidative stress
- heart failure
- prognostic factors
- atrial fibrillation
- brain injury