Both epilepsy and anti-seizure medications affect bone metabolism in children with self-limited epilepsy with centrotemporal spikes.

Xiu-Yu ShiJun JuQian LuLin-Yan HuYa-Ping TianGuang-Hong GuoZhi-Sheng LiuGe-Fei WuHong-Min ZhuYu-Qin ZhangDong LiLi GaoLiu YangChun-Yu WangJian-Xiang LiaoJi-Wen WangShui-Zhen ZhouHua WangXiao-Jing LiJing-Yun GaoLi ZhangXiao-Mei ShuDan LiYan LiChun-Hong ChenXiu-Ju ZhangJian-Min ZhongQiong-Xiang ZhaiYan-Hong SunXue-Feng LinRong-Na RenFei YinYan-Hui ChenFei-Yong JiaZhi-Xian YangJu-Li WangZhe-Zhi XiaLi-Wen WangRong LuoLi-Ping Zou

Published in: Epilepsia (2023)

Epilepsy can affect many aspects of bone metabolism. After controlling epilepsy and other confounders that affect bone metabolism, we found that the effects of ASMs on bone metabolism differed. Oxcarbazepine, levetiracetam, topiramate did not affect bone metabolism, and lamotrigine corrected some of the abnormal markers of bone metabolism in epileptic patients.

Keyphrases

bone mineral density
soft tissue
bone loss
bone regeneration
postmenopausal women
newly diagnosed
end stage renal disease
ejection fraction
peritoneal dialysis
temporal lobe epilepsy
patient reported