Effects of chemotherapy on ovaries of pregnant mice.

Teska Schuurman Ji-Ying Song Vera E R A Wolters Marieke van de Ven Nienke E van Trommel Catharina C M Beerendonk Frédéric Amant Christianne A R Lok

Published in: Archives of gynecology and obstetrics (2022)

Despite physiological ovarian function suppression during gestation, chemotherapy-induced damage of the ovaries occurs in pregnant mouse models, potentially affecting future fertility.

Keyphrases

chemotherapy induced
pregnant women
mouse model
preterm infants
oxidative stress
current status
high fat diet induced
gestational age
squamous cell carcinoma
locally advanced
insulin resistance
skeletal muscle
adipose tissue