The teratogenic effect of pregabalin on heart, liver and kidney in rats: a light microscopic, electron microscopic and immunohistochemical study.
Omnia I IsmailEman S ShaltoutNora Z AbdellahDiab F HettaWael M A Abd El-GhaniLobna A AbdelzaherAhmed Mohamed Mohamed MahmoudAsmaa M HasanNoha A RashedNoha Esmael EbrahemPublished in: BMC pharmacology & toxicology (2022)
PGB at dose of 500 mg/kg revealed minimal toxic changes. PGB cause embryotoxicity in a dose-dependent manner, as the higher dose induced more degenerative changes.