Insights from Leishmania (Viannia) guyanensis in vitro behavior and intercellular communication.

Luiza de Oliveira Ramos PereiraCíntia S SousaHellen C P RamosEduardo C Torres-SantosLiliane S PinheiroMarcelo R AlvesPatricia CuervoGustavo A Sierra RomeroMariana C BoitéRenato PorrozziElisa Cupolillo

Published in: Parasites & vectors (2021)

Data concerning drug sensitivity in the Viannia subgenus are emerging, and L. (V.) guyanensis plays a pivotal epidemiological role in Latin America. Therefore, investigating the parasitic features potentially related to relapses is urgent. Altogether, the data presented here indicate that all tested strains of L. (V.) guyanensis displayed an association between treatment outcome and in vitro parameters, especially the drug sensitivity. Remarkably, sharing enhanced growth ability and decreased drug sensitivity, without intercellular communication, were demonstrated.

Keyphrases

electronic health record
big data
adverse drug
healthcare
emergency department
machine learning
data analysis
health information
artificial intelligence