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METTL14 plays an oncogenic role in NSCLC by modulating ferroptosis and the m6A modification of GPX4.
Yang Lou
Kan Huang
Bo Xu
Xianguo Chen
Published in:
Archives of physiology and biochemistry (2024)
The METTL14/GPX4 axis promotes NSCLC progression by inhibiting cell ferroptosis through the recognition of m6A modification mediated by IGF2BP1.
Keyphrases
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small cell lung cancer
cell death
advanced non small cell lung cancer
signaling pathway
single cell
brain metastases
cell therapy
pi k akt
transcription factor
binding protein
epidermal growth factor receptor
stem cells
cell proliferation