Is it all Lynch syndrome?: An assessment of family history in individuals with mismatch repair-deficient tumors.

Katherine M DempseyRussell BroaddusY Nancy YouSarah Jane NoblinMaureen MorkBryan FellmanDiana UrbauerDiana L UrbauerKaren Lu

Published in: Genetics in medicine : official journal of the American College of Medical Genetics (2014)

MMRD+/germ-line- individuals have less suggestive family histories of LS than individuals with LS. These results imply that MMRD+/germ-line- individuals may not all have LS. This finding highlights the need to determine other causes of MMRD tumors so that these patients and their families can be accurately counseled regarding screening and management.Genet Med 17 6, 476-484.

Keyphrases

ejection fraction
newly diagnosed
case report
patient reported outcomes
patient reported