Prohedonic properties of gamma-hydroxybutyrate are associated with changes in limbic resting-state functional connectivity.

Oliver G BoschFabrizio EspositoDario DornbiererRobin von RotzRainer KraehenmannPhilipp StaempfliBoris B QuednowErich Seifritz

Published in: Human psychopharmacology (2018)

GHB induces prohedonic effects such as euphoria and sexual arousal and in parallel modulates limbic rsFC with areas linked to regulation of mood, cognitive control, and sexual experience. These results further elucidate the drug's effects in neuropsychiatric disorders and as drug of abuse.

Keyphrases

functional connectivity
resting state
mental health
bipolar disorder
emergency department
adverse drug
sleep quality
physical activity
depressive symptoms
intimate partner violence