Use of an aromatase inhibitor in children with congenital adrenal hyperplasia: Impact of anastrozole on bone mineral density and visceral adipose tissue.

Alyssa HalperBelen SanchezJames S HodgesDonald R DengelAnna PetrykKyriakie Sarafoglou

Published in: Clinical endocrinology (2019)

Anastrozole significantly reduced bone age advancement in children with CAH and advanced bone age (>2SDs) without adverse effects on BMD or VAT. Longitudinal studies of anastrozole in children with CAH are needed to validate these findings.

Keyphrases

bone mineral density
postmenopausal women
adipose tissue
young adults
body composition
type diabetes
high fat diet
bone loss
electronic health record