Ginsenoside Rb1 Reduces D-GalN/LPS-induced Acute Liver Injury by Regulating TLR4/NF-κB Signaling and NLRP3 Inflammasome.
Yimei LiuNinghua LiuYujing LiuHongyu HeZhe LuoWenjun LiuNan SongMinjie JuPublished in: Journal of clinical and translational hepatology (2021)
Ginsenoside Rb1 protects mice against D-GalN/LPS-induced ALI by attenuating oxidative stress and the inflammatory response through the TLR4/NF-κB signaling pathway and NLRP3 inflammasome activation.
Keyphrases
- nlrp inflammasome
- inflammatory response
- lps induced
- liver injury
- drug induced
- toll like receptor
- signaling pathway
- oxidative stress
- lipopolysaccharide induced
- induced apoptosis
- pi k akt
- epithelial mesenchymal transition
- dna damage
- high fat diet induced
- nuclear factor
- immune response
- diabetic rats
- metabolic syndrome
- skeletal muscle
- cell proliferation
- endoplasmic reticulum stress
- adipose tissue