Comparison of Reconstruction of Maxilloalveolar Resections in Head and Neck Cancers with Chimeric Anterolateral Thigh Flap (ALT) versus Standard ALT Flap.
Vineet KumarSamreen JaffarMayur MantriAmeya Rajan BinduSaumya MathewsDushyant JaiswalVinay Kant ShankhdharPublished in: Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India (2024)
Background Oral malignancy that presents at a locally advanced stage needs complex surgical resections in which the maxillary cavity is usually left open. The constant maxillary secretions lead to problems like poor healing, fistula formation, and flap necrosis, causing longer hospital stays, delayed adjuvant therapy, and additional surgeries. Several methods have been tried to ameliorate this, each faced with its own difficulties. This study describes the use of chimeric free anterolateral thigh (ALT) with vastus lateralis (VL) muscle to tackle this problem. Materials and Methods With the aim to assess the advantage of reconstruction of maxillo-alveolar resections using chimeric ALT + VL, we analyzed data from 20 cases reconstructed with chimeric free ALT + VL over a year. We compared them with twenty matched controls reconstructed with standard ALT. Analysis was done with respect to intraoperative ease, adequacy of maxillary sinus fill, postoperative secretions, length of hospital stay, duration to adjuvant therapy, and postoperative complications tabulated using the modified Clavien-Dindo classification. Results It was found that chimeric ALT + VL gave greater freedom of movement to plug the maxillary cavity easily. The chimeric arm patients had fewer complications and a shorter mean hospital stay. Most of them received adjuvant therapy within their optimal time window. Conclusion Chimeric ALT with vastus lateralis muscle is a reliable option for reconstructing complex defects, especially with dead space cavities like the maxillary sinus. Effective plugging of the maxillary sinus during the primary surgery results in better patient outcomes and must be done routinely.
Keyphrases
- cell therapy
- cone beam computed tomography
- healthcare
- minimally invasive
- stem cells
- mesenchymal stem cells
- soft tissue
- skeletal muscle
- locally advanced
- machine learning
- squamous cell carcinoma
- end stage renal disease
- patients undergoing
- ejection fraction
- rectal cancer
- adverse drug
- deep learning
- emergency department
- radiation therapy
- clinical trial
- coronary artery disease
- breast reconstruction
- bone marrow
- big data
- peritoneal dialysis
- patient reported outcomes