Association between Opioid Dose, Acute Post-operative Pain and Walking Distance Following Lumbar Spine Surgery.
Kosaku AoyagiJianghua HeMelanie SimpsonBrittany L MeltonSravani ChandakaLemuel R WaitmanNeena K SharmaPublished in: Journal of clinical pharmacy and therapeutics (2019)
The findings indicated that high dose opioids on POD1 did not translate into better outcomes of pain and gait in patients following LSS. In fact, patients in medium and low dose groups walked a greater distance on POD2 and POD3. Use of a functional outcome such as gait should be considered to optimize opioid dose effects.