LncRNA HOTAIR promotes the growth and metastasis of gastric cancer by sponging miR-1277-5p and upregulating COL5A1.

Zhijian WeiLei ChenLei MengWenxiu HanLei HuangAman Xu

Published in: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (2020)

HOTAIR regulates GC growth by sponging miR-1277-5p and upregulating COL5A1, and COL5A1-mediated GC cell proliferation may be mediated by effects on the tumor microenvironment, which provides novel targets for GC treatment.

Keyphrases

cell proliferation
gas chromatography
long non coding rna
mass spectrometry
high resolution
replacement therapy