Efficacy and safety of simultaneous treatment with two biologic medications in refractory Crohn's disease.
Edward YangNicola PanaccioneNatalie WhitmireParambir S DulaiNiels Vande CasteeleSiddharth SinghBrigid S BolandAngelina CollinsWilliam J SandbornRemo PanaccioneRobert BattatPublished in: Alimentary pharmacology & therapeutics (2020)
Dual biologic therapy was associated with clinical, biomarker and endoscopic improvements in selected patients with refractory Crohn's disease who failed multiple biologics. Further studies are needed to validate this approach.