A Multi-center Genome-wide Association Study of Cervical Dystonia.
Yan V SunChengchen LiQin HuiYunfeng HuangRichard BarbanoRamon RodriguezIrene A MalatyStephen ReichKimberly BambargerKatie HolmesJoseph JankovicNeepa J PatelEmmanuel RozeMarie VidailhetBrian D BermanMark S LeDouxAlberto J EspayPinky AgarwalSarah Pirio-RichardsonSamuel A FrankWilliam G OndoRachel Saunders-PullmanSylvain ChouinardStover NatividadAlfredo BerardelliAlexander Y PantelyatAllison BrashearSusan H FoxMeike KastenUlrike M KrämerMiriam NeisTobias BäumerSebastian LoensMax BorscheSimone ZittelAntonia MaurerMathias GelderblomJens VolkmannThorsten OdorferAndrea A KühnFriederike BorngräberInke R KönigCarlos CruchagaAdam C CottonGamze Kilic-BerkmenAlan FreemanStewart A FactorLaura ScorrJ Douglas BremnerViola VaccarinoArshed A QuyyumiChristine KleinJoel S PerlmutterKatja LohmannHyder A JinnahPublished in: Movement disorders : official journal of the Movement Disorder Society (2021)
The genetic underpinnings of cervical dystonia are complex and likely consist of multiple distinct variants of small effect sizes. Larger sample sizes may be needed to provide sufficient statistical power to address the presumably multi-genic etiology of cervical dystonia. © 2021 International Parkinson and Movement Disorder Society.