Stereocontrolled Synthesis of 3-Sulfonyl Chroman-4-ols.
Meng-Yang ChangYu-Lin TsaiPublished in: The Journal of organic chemistry (2018)
The stereocontrolled reduction of 3-sulfonyl chromen-4-ones by two synthetic methods, NaBH4/LiCl and Pd/C/H2, provides two kinds of 3-sulfonyl chroman-4-ols with three contiguous chiral centers under different reaction conditions. The use of various reaction conditions is investigated for efficient transformation.
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