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Ethical issues in the application of genome-wide association studies to US military recruitment and personnel assignments.

Daniel J HurstL A Padilla
Published in: BMJ military health (2024)
Genome-wide association studies seek to associate an organism's genotypes with phenotypes. The goal of such research is to identify specific genetic variants that may be used to predict an individual's risk for a specific physical or mental disease. Recently, it has been recommended that policymakers in the USA should employ genomic surveillance so that it can be used for initial military personnel selection and personnel assignments. However, such a proposal highlights the necessity of subjecting such recommendations to rigorous ethical analysis, including concerns regarding recruitment, transparency and the return of genetic results.
Keyphrases
  • genome wide association
  • mental health
  • case control
  • copy number
  • public health
  • physical activity
  • decision making
  • genome wide
  • clinical practice
  • gene expression
  • data analysis