Au Catalyzing Control Release NO in vivo and Tumor Growth-Inhibiting Effect in Chemo-Photothermal Combination Therapy.

Ying ZhangTianfu ZhouJian LiNuo XuMingze CaiHong ZhangQinfu ZhaoSiling Wang

Published in: International journal of nanomedicine (2021)

The high concentration of NO was found to increase the apoptotic rate and to reduce tumor proliferation. In the chemo-photothermal combination therapy, the tumor inhibition rate was increased up to 94.3%, and Au's contribution from catalyzing NO release NO was 8.17%.

Keyphrases

combination therapy
photodynamic therapy
cancer therapy
signaling pathway
sensitive detection
drug delivery
cell death
drug release
reduced graphene oxide
radiation therapy
quantum dots