Epigenetic Signatures Predict Pathologic Nodal Stage in Breast Cancer Patients with Estrogen Receptor-Positive, Clinically Node-Positive Disease.
Miquel Ensenyat-MendezDennis RüngerJavier I J OrozcoJulie LeJennifer L BakerJoanne WeidhaasDiego M MarzeseMaggie L DiNomePublished in: Annals of surgical oncology (2022)
Epigenetic signatures have an excellent diagnostic accuracy for stratifying nodal disease in patients with clinically positive nodes. Validation of this tool is warranted and may provide an accurate and cost-effective method of identifying patients with predicted low nodal burden who could be spared the morbidity of ALND.