Genomic analysis of Helicobacter pylori in Australia: Antimicrobial resistance, phylogenetic patterns, and virulence factors.

Jonathon P SchubertAlfred TayKhui Hung Claire LeeLex E X LeongChristopher K RaynerMorgyn S WarnerIan C Roberts-ThomsonSamuel P CostelloRobert V Bryant

Published in: Journal of gastroenterology and hepatology (2024)

Refractory H. pylori isolates in Australia emanate from multiple global origins. Strong concordance between genetic and phenotypic antibiotic resistance profiles raises the possibility of utilizing genetic profiling in clinical practice. The dynamic landscape of H. pylori in Australia warrants the establishment of a national database to monitor H. pylori resistance and evolving virulence.

Keyphrases

antimicrobial resistance
helicobacter pylori
clinical practice
helicobacter pylori infection
escherichia coli
genome wide
single cell
pseudomonas aeruginosa
copy number
emergency department
genetic diversity