The metabolic hormone adiponectin affects the correlation between nutritional status and pneumococcal vaccine response in vulnerable indigenous children.
Kris E SiegersAntonius E van HerwaardenJacobus H de WaardBerenice Del NogalPeter W M HermansDoorlène van TienovenGuy A M BerbersMarien I de JongeLilly M VerhagenPublished in: PloS one (2022)
Metabolic hormones, in particular adiponectin, may modify the effect of nutritional status on pneumococcal vaccine response. These findings emphasize the importance of further research to better understand the immunometabolic pathways underlying vaccine response and enable a future of optimal personalized vaccination schedules.